Comprehensive physician-reviewed information about basal cell carcinoma, including warning sign photos, treatment options, symptoms, and risk factors. Comprehensive physician-reviewed information about basal cell carcinoma, In addition, BCC sometimes resembles noncancerous skin conditions such as. Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer. It often appears as a painless raised area of skin, which.
(BCC) Basal Cell Carcinoma
There are no good studies, however, comparing cryosurgery with other modalities, particularly with Mohs surgery, excision, or electrodesiccation and curettage so that no conclusion can be made whether cryosurgery is as efficacious as other methods. Also, there is no evidence on whether curetting the lesions before cryosurgery affects the efficacy of treatment. Electrodesiccation and curettage EDC, also known as curettage and cautery, simply curettage  is accomplished by using a round knife, or curette, to scrape away the soft cancer.
The skin is then burned with an electric current. This further softens the skin, allowing for the knife to cut more deeply with the next layer of curettage. The cycle is repeated, with a safety margin of curettage of normal skin around the visible tumor. Cure rate is very much user-dependent and depends also on the size and type of tumor.
Generally, this method is used on cosmetically unimportant areas like the trunk torso. Some physicians believe that it is acceptable to utilize EDC on the face of elderly patients over the age of However, with increasing life expectancy, such an objective criterion cannot be supported. The cure rate can vary, depending on the aggressiveness of the EDC and the free margin treated. Some advocate curettage alone without electrodesiccation, and with the same cure rate.
Some superficial cancers respond to local therapy with 5-fluorouracil , a chemotherapy agent. Imiquimod may be used prior to surgery in order to reduce the size of the carcinoma. One can expect a great deal of inflammation with this treatment. Some advocate the use of imiquimod prior to Mohs surgery to remove the superficial component of the cancer.
One often waits a month or more after surgery before starting the Imiquimod or 5-fluorouracil to make sure the surgical wound has adequately healed. Some people [ who?
These experimental procedures are not standard care. The study reported that topical IMQ appears effective in the treatment of primary small superficial BCCs but only "may possibly" have a role in the treatment of primary nodular BCC. Approved in , vismodegib is used to treat an advanced form of basal-cell carcinoma. Immunotherapy research suggests that treatment using Euphorbia peplus , a common garden weed, may be effective.
Imiquimod is an immunotherapy but is listed here under chemotherapy. Radiation therapy can be delivered either as external beam radiotherapy or as brachytherapy internal radiotherapy. Although radiotherapy is generally used in older patients who are not candidates for surgery, it is also used in cases where surgical excision will be disfiguring or difficult to reconstruct especially on the tip of the nose, and the nostril rims.
Radiation treatment often takes as few as 5 visits to as many as 25 visits. Usually, the more visits scheduled for therapy, the less complication or damage is done to the normal tissue supporting the tumor. Radiotherapy can also be useful if surgical excision has been done incompletely or if the pathology report following surgery suggests a high risk of recurrence, for example if nerve involvement has been demonstrated.
Usually, recurrent tumors after radiation are treated with surgery, and not with radiation. Further radiation treatment will further damage normal tissue, and the tumor might be resistant to further radiation. Radiation therapy may be contraindicated for treatment of nevoid basal-cell carcinoma syndrome.
A meta-analysis of randomized controlled trials supports radiotherapy as one of the most effective treatments for BCC. Photodynamic therapy PDT is a new modality for treatment of basal-cell carcinoma, which is administrated by application of photosensitizers to the target area. When these molecules are activated by light, they become toxic, therefore destroy the target cells.
Methyl aminolevulinate is approved by EU as a photosensitizer since This therapy is also used in other skin cancer types. Prognosis is excellent if the appropriate method of treatment is used in early primary basal-cell cancers.
Recurrent cancers are much harder to cure, with a higher recurrent rate with any methods of treatment. Although basal-cell carcinoma rarely metastasizes , it grows locally with invasion and destruction of local tissues.
The cancer can impinge on vital structures like nerves and result in loss of sensation or loss of function or rarely death. The vast majority of cases can be successfully treated before serious complications occur. The recurrence rate for the above treatment options ranges from 50 percent to 1 percent or less. Basal-cell cancer is a very common skin cancer. It is much more common in fair-skinned individuals with a family history of basal-cell cancer and increases in incidence closer to the equator or at higher altitude.
There are approximately ,  new cases yearly in the United States alone. In the United States approximately 3 out of 10 caucasians develop a basal-cell carcinoma during their lifetime.
In 80 percent of all cases, basal-cell carcinoma affects the skin of head and neck. Most sporadic BCC arises in small numbers on sun-exposed skin of people over age 50, although younger people may also be affected. The development of multiple basal-cell cancer at an early age could be indicative of nevoid basal-cell carcinoma syndrome , also known as Gorlin's Syndrome.
From Wikipedia, the free encyclopedia. For the skin condition in cats, see Eosinophilic granuloma. Dermoscopy showing telangiectatic vessels.
List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer. Micrograph of a fibroepithelioma of Pinkus. Archived from the original on 5 July Retrieved 30 June The Medical Clinics of North America.
Sometimes the patch crusts. It may also itch or hurt. At other times, it persists with no discomfort. A shiny bump or nodule that is pearly or clear and is often pink, red, or white. The bump can also be tan, black, or brown, especially in dark-haired people, and can be confused with a normal mole. A pink growth with a slightly elevated rolled border and a crusted indentation in the center. As the growth slowly enlarges, tiny blood vessels may develop on the surface.
Sometimes, despite the previous removal of a BCC, the lesion recurs. For this reason it is wise to have your wound assessed a few months after your procedure, as well as on a regular basis, as advised by your doctor. People who have had a previous BCC are at increased risk of getting new ones as well as other skin cancers.
For this reason, a regular complete skin examination by your doctor is advisable, as well as regular self skin examination.
In addition, strict adherence to adequate sun protection measures should be adopted. How We Can Help. Book an appointment at one of our clinics. What is Your Skin Cancer Risk?
Basal cell carcinoma (BCC)
Learn more from WebMD about basal cell carcinoma, the most common type of skin cancer, including its causes, symptoms, treatments, and. Basal cell carcinoma (BCC) is the most common type of skin cancer — and the most common cancer overall. Find out more on treatments, types, and images. Basal cell carcinoma (BCC) is a nonmelanocytic skin cancer (ie, an epithelial tumor) that arises from basal cells (ie, small, round cells found in.